3,271 research outputs found

    Experimental study of the normal zone propagation velocity in double-layer 2G-HTS wires by thermal and electrical methods

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    The Normal Zone Propagation Velocity (NZPV) of a double-layer second generation (2G) high temperature superconducting (HTS) wire manufactured by American Superconductor has been measured by electrical and thermal methods, and the results have been compared and discussed. The NZPV values determined by the voltage traces are ranging from 3.8 mm/s at 0.4 Ic to 19.2 mm/s at 0.9 Ic; while from 5.9 mm/s to 18.3 mm/s by the temperature traces. NZPV determined by these two approaches agrees well with each other. Also, NZPV of double-layer YBCO tape is close to that of conventional single-layer superconducting tape.This work was supported in part by the EPSRC under Grant NMZF/064.This is the accepted manuscript. The final version is available from IEEE at http://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=6963291&sortType%3Dasc_p_Sequence%26filter%3DAND%28p_IS_Number%3A6353170%29%26rowsPerPage%3D50

    Investigation of demagnetization in HTS stacked tapes implemented in electric machines as a result of crossed magnetic field

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    This paper investigates the practical effectiveness of employing superconducting stacked tapes to superconducting electric machinery. The use of superconducting bulks in various practical applications has been addressed extensively in the literature. However, in practice, dramatic decrease in magnetization would occur on superconducting bulks due to the crossed field effect. In our study, we employed the superconducting stacked tapes in a synchronous superconducting motor, which was designed and fabricated in our laboratory, aiming to lessen demagnetization due to crossed field effect in comparison with superconducting bulks. Applying the transverse AC field, the effects of frequency, amplitude, and number of cycles of the transverse magnetic field are discussed. Furthermore, a stack of 16 layers of superconducting tapes is modelled and the consequences of applying the crossed magnetic field on the sample are evaluated. The confrontation between experiments and simulation allows us to thoroughly understand the crossed field effects on stacked tapes. At the end, a preventive treatment, based on the shielding characteristic of superconductor and materials with high permeability, i.e. -metal and metalic glass, is suggested. On the other hand, the shielding feature of aforementioned materials will hinder the penetration of magnetic field and, consequently, reduction of the demagnetization will be attained.This is the accepted manuscript. The final version is available from IEEE at https://ieeexplore.ieee.org/xpl/articleDetails.jsp?arnumber=6965587&sortType%3Dasc_p_Sequence%26filter%3DAND%28p_Publication_Number%3A77%29%26pageNumber%3D16

    Study protocol of cost-effectiveness and cost-utility of a biopsychosocial multidisciplinary intervention in the evolution of non-specific sub-acute low back pain in the working population: cluster randomised trial.

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    This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Background: Low back pain (LBP), with high incidence and prevalence rate, is one of the most common reasons to consult the health system and is responsible for a significant amount of sick leave, leading to high health and social costs. The objective of the study is to assess the cost-effectiveness and cost-utility analysis of a multidisciplinary biopsychosocial educational group intervention (MBEGI) of non-specific sub-acute LBP in comparison with the usual care in the working population recruited in primary healthcare centres. Methods/design: The study design is a cost-effectiveness and cost-utility analysis of a MBEGI in comparison with the usual care of non-specific sub-acute LBP.Measures on effectiveness and costs of both interventions will be obtained from a cluster randomised controlled clinical trial carried out in 38 Catalan primary health care centres, enrolling 932 patients between 18 and 65 years old with a diagnosis of non-specific sub-acute LBP. Effectiveness measures are: pharmaceutical treatments, work sick leave (% and duration in days), Roland Morris disability, McGill pain intensity, Fear Avoidance Beliefs (FAB) and Golberg Questionnaires. Utility measures will be calculated from the SF-12. The analysis will be performed from a social perspective. The temporal horizon is at 3 months (change to chronic LBP) and 12 months (evaluate the outcomes at long term. Assessment of outcomes will be blinded and will follow the intention-to-treat principle. Discussion: We hope to demonstrate the cost-effectiveness and cost-utility of MBEGI, see an improvement in the patients' quality of life, achieve a reduction in the duration of episodes and the chronicity of non-specific low back pain, and be able to report a decrease in the social costs. If the intervention is cost-effectiveness and cost-utility, it could be applied to Primary Health Care Centres. Trial registration: ISRCTN: ISRCTN5871969

    Doctors and nurses benefit from interprofessional online education in dermatology

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    <p>Abstract</p> <p>Background</p> <p>Benefits of online learning in the health sector have been demonstrated in previous studies. We examined the potential benefits of a joint web-based curriculum on atopic eczema for health personnel.</p> <p>Methods</p> <p>Enrolled doctors and nurses had access to the curriculum for 8 weeks. After the course learners completed a questionnaire. Two dermatologists rated the quality of the submitted homework assignments. Based on data from the project's budget and the Norwegian Medical Association, we estimated the saved travel expenses.</p> <p>Results</p> <p>Eighty-eight learners (46 doctors) registered for the course. We received 55 questionnaires (response rate 63%). Twenty-seven learners (31%; 16 doctors, 11 nurses; χ<sup>2 </sup>= 0.03; P = 0.87) used the discussion forum. We found no significant differences in the total questionnaire scores between doctors and nurses. The homework assignments were given an average score of 3.6 for doctors and 3.5 for nurses (P = 0.8) by rater 1. Rater 2 scored 3.9 and 3.6 for doctors and nurses respectively (P = 0.2). The break-even between travel/hotel expenses and course development costs occurred at 135 saved travel refund applications.</p> <p>Conclusions</p> <p>Doctors and nurses were equally satisfied with a joint web-based course on atopic eczema. The use of an online discussion forum was limited but similar between doctors and nurses. There were no significant differences in the quality of submitted homework assignments. The cost of developing the course was 716 841 NOK and the first 86 learners saved 455 198 NOK in travel expenses.</p

    Evidence of the Importance of Host Habitat Use in Predicting the Dilution Effect of Wild Boar for Deer Exposure to Anaplasma spp

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    Foci of tick-borne pathogens occur at fine spatial scales, and depend upon a complex arrangement of factors involving climate, host abundance and landscape composition. It has been proposed that the presence of hosts that support tick feeding but not pathogen multiplication may dilute the transmission of the pathogen. However, models need to consider the spatial component to adequately explain how hosts, ticks and pathogens are distributed into the landscape

    Bcl-2 protein family: Implications in vascular apoptosis and atherosclerosis

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    Apoptosis has been recognized as a central component in the pathogenesis of atherosclerosis, in addition to the other human pathologies such as cancer and diabetes. The pathophysiology of atherosclerosis is complex, involving both apoptosis and proliferation at different phases of its progression. Oxidative modification of lipids and inflammation differentially regulate the apoptotic and proliferative responses of vascular cells during progression of the atherosclerotic lesion. Bcl-2 proteins act as the major regulators of extrinsic and intrinsic apoptosis signalling pathways and more recently it has become evident that they mediate the apoptotic response of vascular cells in response to oxidation and inflammation either in a provocative or an inhibitory mode of action. Here we address Bcl-2 proteins as major therapeutic targets for the treatment of atherosclerosis and underscore the need for the novel preventive and therapeutic interventions against atherosclerosis, which should be designed in the light of molecular mechanisms regulating apoptosis of vascular cells in atherosclerotic lesions

    Reuse of terminological resources for efficient ontological engineering in Life Sciences

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    This paper is intended to explore how to use terminological resources for ontology engineering. Nowadays there are several biomedical ontologies describing overlapping domains, but there is not a clear correspondence between the concepts that are supposed to be equivalent or just similar. These resources are quite precious but their integration and further development are expensive. Terminologies may support the ontological development in several stages of the lifecycle of the ontology; e.g. ontology integration. In this paper we investigate the use of terminological resources during the ontology lifecycle. We claim that the proper creation and use of a shared thesaurus is a cornerstone for the successful application of the Semantic Web technology within life sciences. Moreover, we have applied our approach to a real scenario, the Health-e-Child (HeC) project, and we have evaluated the impact of filtering and re-organizing several resources. As a result, we have created a reference thesaurus for this project, named HeCTh
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